Overview
Knot theory is the branch of Low Dimensional Topology concerned with the study of the configuration of circles embedded in the three-dimensional space. The early years of this theory were primarily driven by its application in chemistry. More recently, the discovery of knotted DNA molecules by biologists brought intense attention to knot theory. Collaboration between cell biologists and knot theorists shows that the theory can be successfully used to build robust mathematical models for the action of certain enzymes on circular DNA molecule.